Publications 2025

Competition between glycine and GABA_A receptors for gephyrin controls their equilibrium populations at inhibitory synapses. Kostrz D, Maynard SA, Camuso S, Schulte C, Laurent F, Masson JB, Maric HM, Gosse C, Triller A, Strick TR, Specht CG. Proc Natl Acad Sci U S A. 2025 Dec 30;122(52):e2500226122. https://doi.org/10.1073/pnas.2500226122
Tau seeding activity in the cerebrospinal fluid of Alzheimer disease patients predicts short-term cognitive decline. Houzé L, Dhenain M, Lam S, Petit F, Haïk S, Mouton-Liger F, Hugon J, Dam J, Paquet C, Jockers R, Cecon E. Alzheimers Res Ther. 2025 Jul 2;17(1):145. https://doi.org/10.1186/s13195-025-01792-w.
Resveratrol does not mimic the positive effects of calorie restriction on lifespan in Microcebus murinus. Pifferi F, Terrien J, Marchal J, Dal-Pan A, Djelti F, Perret M, Epelbaum J, Blanc S, Picq JL, Dhenain M, Aujard F. Commun Biol. 2025 Feb 28;8(1):331. https://doi.org/10.1038/s42003-024-07387-9
[Towards using pseudo-prions against neurodegenerative diseases]. Dhenain M, Celestine M, Jacquier-Sarlin M, Buisson A. Med Sci (Paris). 2025 Apr;41(4):318-320. https://doi.org/10.1051/medsci/2025055
Loss of the neuronal kinase DCLK3 leads to anxiety-like behaviour and memory deficits. de Longprez L, Gaillard MC, Decraene C, Pérot JB, Keime C, Nadkarni N, Louça M, Jan C, Liot G, Aurégan G, Guillermier M, Mitja J, Hantraye P, Bertaux F, Norbert M, Bonvento G, Flament J, Dhenain M, Néri C, Bemelmans AP, Mérienne K, Cambon K, Brouillet E. Brain. 2025 Jul 7;148(7):2453-2468. https://doi.org/10.1093/brain/awaf042
Contributions of connectional pathways to shaping Alzheimer’s disease pathologies. Bougacha S, Roquet D, Landeau B, Saul E, Naveau M, Sherif S, Bejanin A, Dhenain M, Raj A, Vivien D, Chetelat G. Brain Commun. 2025 Jan 6;7(1):fcae459. https://doi.org/10.1093/braincomms/fcae459
Revisiting the role of sexual hormones in the demyelinated central nervous system. Traiffort E, Kassoussi A, Zahaf A. Front Neuroendocrinol. 2025 Jan;76:101172. https://doi.org/10.1016/j.yfrne.2024.101172
Crosstalk between androgen signaling and the chemokine receptor CXCR4: a novel strategy to promote myelin regeneration. Bardy-Lagarde M, Asbelaoui N, Ghoumari AM. Neural Regen Res. 2025 Sep 1;20(9):2581-2582. https://doi.org/10.4103/NRR.NRR-D-24-00439
From sex hormone decrease to hormonal treatment: impacts on cardiovascular risk with ageing. Fontaine C, Gosset A, Davezac M, Buscato M, Grouthier V, Renault MA, Henrion D, Trémollières F, Schumacher M, Lenfant F, Arnal JF. Cardiovasc Res. 2025 Aug 14:cvaf086. https://doi.org/10.1093/cvr/cvaf086
Multiple sclerosis lesions exhibit sex-specific steroid changes. Luchetti S, Mason MRJ, Liere P, Pianos A, Cossu S, Hofstee M, Sluiter A, Adelia, van Scheppingen J, Aronica E, Schumacher M, Huitinga I. Neurobiol Dis. 2025 Jul 22;214:107040. https://doi.org/10.1016/j.nbd.2025.107040
The translocator protein 18 kDa (TSPO) ligand etifoxine in an animal model of anxiety: Line- and sex-dependent effects on emotionality, stress reactivity, spine density, oxytocin receptors, steroids, and microbiome composition. Fischer L, Paschke B, Gareis F, Schumacher M, Liere P, Hiergeist A, Gessner A, Rupprecht R, Neumann ID, Bosch OJ. Neuropharmacology. 2025 Mar 15;266:110282. https://doi.org/10.1016/j.neuropharm.2024.110282
Structural remodeling of the brain cortex and functional recovery following hypoglossal-facial neurorrhaphy in patients with facial paralysis. Wang B, Ling M, Guo C, Sun S, Zhang X, Hu C, Liu H, Li D, Schumacher M, Sui B, Liu S. Brain Res. 2025 Feb 15;1849:149437. https://doi.org/10.1016/j.brainres.2024.149437
Mild TBI changes brain and plasma neurosteroid levels in mice. Umeasalugo KE, Khalin I, Seker B, Liere P, Pianos A, Sanchez-Garcia M, Schumacher M, Koerte IK, Plesnila N. Neurotrauma Rep. 2025 Jan 20;6(1):39-52. https://doi.org/10.1089/neur.2024.0151
Identification of low copy synaptic glycine receptors in the mouse brain using single molecule localisation microscopy. Camuso S, Vella Y, Youjil Abadi S, Mille C, Brône B, G Specht CG. BioRxiv. 2025. https://doi.org/10.1101/2025.01.07.631736
Oral phenotype in SATB2-associated syndrome: cross-sectional study of the French cohort. Vegas N, Rio M, Adnot P, Soupre V, Petit F, Ghoumid J, Toutain A, Dieterich K, Marey I, Gilbert-Dussardier B, Le Guyader G, Francannet C, Schaefer E, Perrin L, Nizon M, Beneteau C, Genevieve D, Willems M, Faivre L, Grimaldi M, Melki J, Stoeva R, Putoux A, Pons L, Benistan K, Amiel J, Abadie V. Orphanet J Rare Dis. 2025 Jun 5;20(1):278. https://doi.org/10.1186/s13023-025-03609-3
Autocrine interferon poisoning mediates ADAR1-dependent synthetic lethality in BRCA1/2-mutant cancers. Chabanon RM, Shcherbakova L, Lacroix-Triki M, Aglave M, Zeghondy J, Kriaa V, Gougé A, Garrido M, Edmond E, Bigot L, Krastev DB, Brough R, Pettitt SJ, Thomas-Bonafos T, Samstein R, Massard C, Deloger M, Tutt AN, Barlesi F, Loriot Y, Delaloge S, Tawk M, Degerny C, Lin YL, Pistilli B, Pasero P, Lord CJ, Postel-Vinay S. Nat Commun. 2025 Jul 29;16(1):6972. https://doi.org/10.1038/s41467-025-62309-5
Schwann cells have a limited window of time in which to initiate myelination signaling during early migration in vivo. El-Hage O, Mikdache A, Boueid MJ, Degerny C, Tawk M. Cells Dev. 2025 Mar;181:203993. https://doi.org/10.1016/j.cdev.2024.203993
Characterizing extracellular vesicles of human fungal pathogens. Rodrigues ML, Janbon G, O’Connell RJ, Chu TT, May RC, Jin H, Reis FCG, Alves LR, Puccia R, Fill TP, Rizzo J, Zamith-Miranda D, Miranda K, Gonçalves T, Ene IV, Kabani M, Anderson M, Gow NAR, Andes DR, Casadevall A, Nosanchuk JD, Nimrichter L. Nat Microbiol. 2025 Apr;10(4):825-835. https://doi.org/10.1038/s41564-025-01962-4
Loss of the neuronal kinase DCLK3 leads to anxiety-like behaviour and memory deficits. de Longprez L, Gaillard MC, Decraene C, Pérot JB, Keime C, Nadkarni N, Louça M, Jan C, Liot G, Aurégan G, Guillermier M, Mitja J, Hantraye P, Bertaux F, Norbert M, Bonvento G, Flament J, Dhenain M, Néri C, Bemelmans AP, Mérienne K, Cambon K, Brouillet E. Brain. 2025 Jul 7;148(7):2453-2468. https://doi.org/10.1093/brain/awaf042
Normal aging increases white matter microglial reaction and perivascular macrophages in the microcebe primate. Dupuis L, Garcia L, Petit F, Lam S, Hirbec H, Picq JL, Boche D, Dhenain M. BioRxiv 2025.03.26.645519; https://doi.org/10.1101/2025.03.26.645519
Tips and tricks of spinal cord biopsy: insights from a multicenter series of 61 patients. Mallereau CH, Dannhoff G, Todeschi J, Severac F, Aghakhani N, Parker F, Benali A, Ganau M, Hamdan N, Le Van T, Cebula H, Proust F, Chaussemy D, Moruzzi F, Carangelo BR, Zalaffi A, Cardia A, Zaed I, Spatola G, Bruno C, Tini P, Giacomo AMD, Cerase A, Gualtieri G, Knafo S, Chibbaro S. J Neurooncol. 2025 Jul;173(3):719-729. https://doi.org/10.1007/s11060-025-05009-w
In reply: A staged approach for surgical management of basilar invagination. Knafo S. Oper Neurosurg. 2025 Jun 1;28(6):907-908. https://doi.org/10.1227/ons.0000000000001544
Upper end of the central canal of the human spinal cord: Quantitative anatomical study and 3D modeling. Lefevre E, Quang ML, Chotard G, Knafo S, Mengelle P, Taupin Y, Liguoro D, Jecko V, Vignes JR, Roblot P. Clin Anat. 2025 Jan;38(1):35-42. https://doi.org/10.1002/ca.24196